Hylocereus undatus grows best in dry, tropical or subtropical climates, it need full sun to partial shade. Shade is sometimes provided in hot climates. The plants aren't usually too picky as to soil type, but because of their epiphytic nature, it is recommended to grow them in well-drained soil mix that is supplemented with high amounts of organic material. During the growing season (March-August), the plants are watered on a regular basis, making sure that they never dry out completely. They are fertilized on a monthly basis with a balanced fertilizer during this period. In late August, water is restricted to about once a week until January. Night temperatures at this time should be about 10° C. In January or February, watering is stopped for a period of 4 weeks to aid in flower formation. In March, regular watering is resumed and the plant will flower in 6 to 8 weeks. Will tolerate temperatures to 45° C, and short periods of frost, but prolonged cold will damage or kill the plant.