Caralluma speciosa is relatively easy to grow. It needs regular watering, especially during the hottest summer days; provide also some light watering if the green house temperatures in winter are elevated. Either excessive or very scarce watering can induce rot.
Frost Tolerance: Winter temperatures must be kept over 10° C. But it can withstand winter night-time temperatures down to about 5°(or less) Celsius for short period. Freezing temperatures are fatal. 
Sun Exposure: Full sun to half sun. It has a great advantage if grown in very strong light, but sheltered from full sun.